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Peripheral ameloblastoma, a rare and unusual variant of odontogenic tumor, representing 1% of all ameloblastomas. The extraosseous location is the peculiar feature of this type of tumor, which is otherwise similar to the classical ameloblastoma. This paper describes a case of peripheral ameloblastoma in a 43-year-old female affecting the left retromolar pad area of the mandible which was clinically diagnosed as a pyogenic granuloma. Histologically, the tumor showed of follicular ameloblastoma in continuity with a surface oral epithelium.